True or False: In the U.S., no pesticide can be sold or used without federal registration.

The assertion that in the U.S., no pesticide can be sold or used without federal registration is indeed true. This requirement is set forth by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), which mandates that all pesticides must be evaluated and approved by the Environmental Protection Agency (EPA) before they can be marketed or used. The registration process ensures that pesticides meet safety, efficacy, and environmental standards, protecting both public health and the environment.

This rigorous regulation means that even for pesticides intended for personal or non-agricultural use, or those that are marketed as "natural," federal registration is still necessary. The requirement applies uniformly across all categories of pesticides, not just those used in agricultural settings or those considered regulated. As a result, this statement accurately reflects the key regulatory framework governing the use of pesticides in the United States.